Tamara Abalde was the star for the Spanish as she totalled 15 points and seven rebounds to help dump the Eastern European side out of the tournament.
The first quarter began with a flourish as Abalbe opened her account with just 12 seconds gone, but Lithuania responded in style with a three-pointer from Vitalija Vasciunaite.
That was set to be the best of the action however as the Spanish ended the period with an 18-11 lead as the Lithuanians were left scrapping for free-throw points.
In the second session Spain stamped their authority on the contest by racing into a 33-15 lead after putting up 11 unanswered points at the start of the quarter.
The Lithuanians showed some spirit and fought back to take the third quarter 17-12 with Sarune Povilionyte and Laima Rickeviciute both scoring from behind the charity stripe on their way to eight-point hauls.
It was Spain though who eased to victory in the final session winning it 24-14 despite the efforts of Marina Solopova, who scored nine of her 15 points for Lithuania
in a late flourish.